In daily life, people with diabetes may need to take other drugs for a long time. Some of these drugs may cause blood sugar to rise or become unstable, which may have a certain negative impact on blood sugar control. Therefore, diabetic patients need to take the following eight drugs. Be extra cautious.
Hormone drug
Glucocorticoids, birth control pills, auxins, etc. can cause elevated blood sugar. Glucocorticoids can promote gluconeogenesis, slow down the decomposition of glucose and reduce the body's use of glucose, thereby increasing blood sugar levels and reducing glucose tolerance. .
The contraceptive can reduce the absorption of glucose by peripheral tissues and raise blood sugar. In addition, auxin and insulin are mutually antagonistic in function. Long-term use of auxin can cause insulin resistance in peripheral tissues, thereby raising blood sugar.
2. Sympathomimetic drugs
For example, salbutamol causes the glycogen stored in the liver and skeletal muscle to decompose, leading to an increase in blood sugar. However, when these drugs are administered by aerosol inhalation, they have less effect on blood glucose fluctuations in inhalers.
3. Partial hypolipidemic drugs
Niacin (also known as vitamin B3), while lowering blood lipids, increases insulin resistance and inhibits the use of glucose by tissues, thereby producing a certain effect of raising blood sugar.
Reminder: While statins lower cholesterol, they also have a tendency to cause elevated blood sugar.
4. Some antihypertensive drugs
Diuretics and beta blockers in antihypertensive drugs can affect patients' blood glucose levels. Thiazide diuretics such as hydrochlorothiazide have a greater impact on glucose tolerance and have toxic effects on B cells, leading to hypokalemia in patients. It also inhibits insulin secretion.
Diabetes patients should try to avoid the use of thiazide diuretics. Beta blockers, such as metoprolol, induce blood sugar elevation by inhibiting insulin secretion and tissue utilization of glucose. use.
5. Immunosuppressants
Such as cyclosporine A, tacrolimus, etc., may lead to necrosis of the islet cells, vacuolar-like lesions, resulting in decreased insulin secretion, and increased insulin resistance in the body to increase blood sugar.
This kind of adverse reaction is closely related to the time of administration and the dose.
6. Antipsychotics
Such as chlorpromazine, haloperidol, clozapine, sulpiride, olanzapine, risperidone, etc., can cause insulin resistance in the body, which causes high blood sugar, which is the most obvious effect of chlorpromazine on blood sugar.
7. Protease inhibitors
Such as nelfinavir, Shaqinbangwei, etc., after antiviral treatment and for a long time, may induce hyperglycemia.
Patients should be tested for basal blood glucose levels between 3 and 4 months before treatment and during the first year of treatment. If the patient's blood glucose is stable, the number of tests can be gradually reduced.
8. Anti-tuberculosis drugs
4. Drugs such as isoniazid, rifampicin, amiodarone can also cause blood sugar to rise.
In addition, the quinolone antibiotic Gatifloxacin may cause fluctuations in blood sugar levels.
