On July 23, 2018, Waters Corporation, Prosolia and the Purdue Research Foundation (PRF) announced that Waters has obtained electrospray desorption ionization of Prossia and PRF for all mass spectrometry applications ( DESI) Technology exclusive rights.
Waters SYNAPT G2-Si HD Mass Spectrometer with DESI ion source
Waters Corporation Chairman and CEO Chris O'Connell said: 'Today, mass spectrometry technology is increasingly used in biomedical research and related fields. Waters further enriched its mass spectrometry imaging with the acquisition of DESI technology. Product range. Compared to traditional histopathological imaging techniques, DESI mass spectrometry provides complementary and more instructive data. In addition, one of the major advantages of this technology is the ability to analyze the molecular fingerprints of samples and assist researchers in discovering them. A deeper understanding of biology ultimately helps us better understand the disease and develop more effective and innovative medical therapies.'
DESI imaging technology by applying a certain high voltage by attaching a spray solvent to the capillary, forming a charged spray droplet with the aid of nitrogen, bombarding the surface of the sample, simultaneous electrolysis and dissociation of the charged solvent and the analyte, after desolvation , along the transfer capillary into the mass spectrometer for analysis.
Prosolia CEO Justin Wiseman said: 'Prosolia is very proud of the development and commercialization of DESI technology. We are very proud of this. DESI technology not only provides high quality data, but also requires very little sample preparation. A non-destructive technology that allows multimodal analysis with just one sample and has immeasurable application potential in mass spectrometry.
DESI technology was developed by a team led by R. Graham Cooks, Distinguished Professor of Purry University Henry Bohn Hass. While acquiring Prosolia DESI technical intellectual property and obtaining a PRF license, Waters and Purdue University were also established under the terms of the new license agreement. Another collaborative project, Waters, will provide Purd University with the Synapt G2-Si time-of-flight mass spectrometer for further research into the application of DESI technology.
Dr. Cooks commented: 'This acquisition decision is an important milestone in the continued development of DESI technology and will benefit global scientists. We congratulate the achievements of the Justin and Prosolia teams and look forward to working with Waters to open DESI in the future. A new chapter in technology! '
Waters will continue to support customers already equipped with DESI technology for Xevo and Synapt time-of-flight mass spectrometers. Prosolia will remain on September 30, 2019 as the technology moves from Prosolia to Waters. Continued to provide DESI technology for non-Waters mass spectrometers. In addition, for those scientists and research organizations that have purchased non-Waters mass spectrometers equipped with DESI ion sources, Prosolia's warranty before the acquisition of DESI technology by Waters The promise continues to be valid. For more details, please visit the Prosolia website: https://prosolia.com/.