Recently, a new paper published in the journal Cell Metabolism reminds people to pay attention to the intake of fatty foods, which may lead to obesity.
Researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences in Beijing and the University of Aberdeen in the UK believe that this is by far the largest of its kind. They tested carbohydrates, fats and proteins. The effect of a large number of nutrients on body fat accumulation.
The scientists turned to the mouse model because, as they explained, it was tricky to ask human participants to follow a diet and evaluate them for a long time. But observe rodents - they are similar Metabolic mechanism - can provide key clues and feasible evidence.
Mice belonging to five different genetically engineered strains were assigned to one of 30 different types of diets, including changes in their fat, carbohydrate and protein content. These mice were kept in their diet for 3 months, respectively. Equivalent to humans for 9 years. During this time, they assessed changes in body weight and body fat content to determine which mice eventually became overweight.
Scientists have found that only excessive intake of fat increases the body's obesity (body fat content), while carbohydrates - including up to 30% of the sugar source of calories - have no effect.
In addition, a mixed diet of fat and sugar does not increase body fat than the fat diet itself.
As for protein intake, the research team said that there is no evidence that it will affect the intake of other macronutrients or the amount of body fat.
Why does fat intake lead to obesity? Researchers believe that fat 'attracts' the brain's reward system, stimulating a desire for excess calories, and thus determining weight gain.
The obvious limitation of this study is that it is based on mice rather than humans. However, mice have many similarities with humans in terms of physiology and metabolism, and we will never do such research: the human diet is in such a long period. Received the same control during the time.
