The picture shows Chen Xin, a researcher at the School of Chemical Engineering, Xi'an Jiaotong University, explaining the research results.
'The construction of intelligent controlled-release materials can successfully solve the precise treatment of diseases such as tumors, infectious diseases, immune diseases, and biomedical problems such as efficient induction and regeneration of bones, skin, teeth and other tissues. 'Chen Xin 29, Research Fellow, School of Chemical Engineering, Xi'an Jiaotong University Japan said that this technology will be used in the future, such as beauty, heightening and other applications.
It is understood that chemotherapy is currently one of the main means of treating cancer. Traditional chemotherapy is less effective and has obvious side effects. Intelligent controlled release materials are like the 'alarm clock' of 'control drug release', which is controlled according to the environmental response of the lesion. Release or not, release rate and release degree. It has the advantages of being able to load bioactive drugs in large quantities, protecting active pharmaceutical ingredients, improving drug bioavailability and helping drug targeting.
Chen Xin said that intelligent controlled-release materials are considered to be an important development direction in the field of modern biomedicine. They are receiving more and more attention in the fields of disease treatment and tissue regeneration. How to pass the complexity and variability of clinical diseases Intelligent controlled-release materials to achieve precise drug delivery that fully meets physiological needs is still a problem that plagues clinical medicine.
Through the design and functionalization of nano drug carriers, the research team introduced advanced concepts such as chemotherapy, photothermal therapy, targeted therapy and visual therapy into the treatment of oral cancer, and constructed a smart tumor treatment micro-nano device. Effective treatment and accurate labeling of oral cancer and other cancers, and long-term inhibition of recurrence, significantly improved patient survival.
According to reports, the team prepared a micro-nano composite scaffold with biomimetic structure and growth factor carrier, which realized large-area non-returned bone and complete repair of skin defects. Constructed a tumor micro-environment-responsive nanocomposite scaffold, which can be used after surgery. Reactive tumor cells around the responsive release of tumor-targeted nano drug carriers, accurately kill tumor cells and inhibit tumor metastasis without affecting healthy cells.
The researchers said that the related design reduces the damage to the donor cells during the treatment process, so that the pre-loaded stem cells still have differentiation and regeneration potential after tumor treatment, thus achieving the integration of tumor treatment tissue regeneration.
'This technology is also very practical in life, can make the mask better absorbed, so that bone growth can be increased.' Chen Xin told reporters that the technology has been used in some applications and enterprises, including medical, beauty , health care and other fields.
