Read Now: New Technology Can Print 3D Human Tissues with Microvessels Faster | New Technology Can Print 3D Human Tissues with Microvessels Faster

According to foreign media New Atlas, Prellis Biologics has developed a fast, high-resolution 3D printing technology that can print live tissue containing micro-vessels. New technology enables cells to acquire enough oxygen while building complex structures And nutrients to sustain life.

According to the U.S. government, of the more than 114,000 people waiting for organ transplants in the country, 20 die each day. This is mainly due to the long-term shortage of donors and there are not enough organs available. Printing live tissues involves placing biota. A scaffold of a capacitive material (such as a hydrogel), which represents a connecting material that normally holds organ cells in place, these cells colonize the scaffold and organize into the proper tissue. The problem is that the body cells need continuous supply of oxygen and nutrients, If they are deprived, they will die in about 30 minutes. To prevent this, living tissue needs to have a complex network of micro-vessels that can provide oxygen to cells.

Currently 3D printing of one cubic centimeter of human tissue may take several weeks. Even if the printer contains microvessels in the structure, the tissue is still a large number of dead cells for a long time before completion, so the usual technique is to print the tissue in a very thin On thin slices, these flakes can be continuously soaked in flowing nutrients.

Prellis's method is to use a holographic printing technology with a resolution of 0.5 micron, which is 10 times smaller than a conventional bioprinter, to work full-function organs at a speed of 1000 times faster. In other words, when an infrared laser is used to rapidly cure a hydrogel When the stent's optical support system is complete, it will be able to print a tissue and its entire vascular system in less than 12 hours.

Dr. Melanie Matheu, CEO and co-founder of Prellis Biologics, stated: 'The speed we can achieve is limited only by the configuration of optical systems. We are exploring the development of customized optical systems, which will greatly enhance our capabilities, our ultimate goal. The complete renal vasculature is printed in 12 hours or less.'

Prellis said that if the company can provide 3D-printed organs, it will not only have a major impact on the transplant, but it can also reduce medical costs by reducing the need for oxygen systems, dialysis, insulin injections and similar treatments. It will also have Helps in drug development and toxicology screening.

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