Ten of the medical device industry | 'Unicorn' | Who has more investment value?

Medical Network, June 14 Today, the beginning and continuation of medical device companies should not monopolize or profit for the ultimate goal of becoming a unicorn, but should continue to use innovation as a process to improve human health. , Make life better.

In recent days, news about all walks of life unicorns flew like snowflakes, and entrepreneurial networks in all walks of life transformed into a unicorn enterprise in all fields. Mostly like a spring night, unicorns Tide to come' feeling.

The concept of unicorns spreading from the mobile internet field began to infiltrate into all walks of life. The definition and evaluation criteria of unicorns are not limited, and people can not help but feel that: Unicorns have to be played badly.

There was a wind of 'fighting against beasts' on the Internet. Discussion on the definition and standard of unicorns became a new trend in the industry.

Today, we will have a good chat with the Unicorn and take a look at the 10 unicorns in the healthcare industry.

In 2013, Aileen Lee left Kleiner Perkins, a well-known venture capital firm that had worked for more than a decade, and founded his own company, Cowboy Ventures. At the TechCrunch International Innovation Summit in November 2013, Irene Lee published Welcome to the Unicorn Club: Learning a Billion-Dollar Startup” presentation of the concept of 'Unicorn'.

The unicorn refers to startups that are valued at more than US$1 billion. Subsequently, the term unicorn became popular immediately, quickly spread on Twitter and blog posts, and was used by many investors and founders for weeks. Inside, the unicorn became a common term in Silicon Valley.

In subsequent discussions with Unicorns, the founding executive director of Singularity University, the global ambassador of Singular University, Salem Ismail, "The Index Organization: The 11 strongest attributes for the creation of Unicorn. And Al Radamant, the founder of Silicon Valley consulting company Play Bigger, “Become a Unicorn: Pirates, Dreamers, How Innovators Create and Lead New Products”, and profoundly expounds the 'unicorn' from multiple dimensions. The former studies and summarizes the 11 internal and external important features of the global "unicorn" enterprise from the index organization.

Unlike Salim Ismail, "Becoming a Unicorn" analyzes the secret of the "unicorn" enterprise as a unicorn from the perspective of the category. The reason why the "unicorn" is a unicorn is The key to beast is not to subvert, but to innovate and to meet the needs of users (customers).

As venture capitalist Xu Xiaoping said: If there really is any secret to success as a unicorn, it must be through your innovation that your company has solved a pain point that has been plaguing people for a long time, giving people an unprecedented experience. Bring the discussion and understanding of 'Unicorn' back to the avenue.

Coincidentally, on the evening of May 27, Dr. Yang Zhengda, founder and CEO of iTutorGroup, was a guest. First Financial "Brainstorming" believed that innovation is a prerequisite for becoming a unicorn enterprise.

Only by building barriers to competition through innovation, continuing to widen and deepen the moat, and always maintaining the entrepreneurial spirit, can it be regarded as a truly unicorn enterprise. There is no doubt that the current 'unicorns' are mainly divided into two types: Capital-driven. Unicorns and unicorns driven by technological innovations, but the two are essentially different.

Companies that rely too heavily on capital often win the market by burning money. It is difficult to build their own moat, and they are easily overtaken by competitors. Unicorns that have grown up through technological innovation can truly realize the long-term success of the industry.

It confirms Dave Peterson’s description in the book “Becoming a Unicorn”: “The most intriguing company sells not better but differently. This difference may be called subversion in the technology industry or innovation”. This is the charm and value of the unicorn. From this, we will be based on the 'technology and innovation driven' as the standard, inventorying the 10 domestic medical equipment 'unicorn' companies that deserve attention.

According to the evaluation dimension of 'Technology and Innovation', the author took a look at the top ten unicorn medical equipment manufacturers in China. They are each in the field of subdivision of medical devices, with technology-driven innovation, and have made outstanding products.

Without exception, these unicorns maintained more than 8% of R&D investment (accounting ratio), and some of them also maintained R&D investment of 20% to 30%, and they continued to increase each year.

What is being released here is the courage and ambition of companies for technology and innovation. Companies that shouted “rejuvenating the national medical care” but kept less than 4% of R&D investment are without exception exceptions. The only way to innovate is to Talent + investment, Today we will take a look at 10 domestic medical equipment industry unicorn company.

Shanghai Lian Ying was established in October 2010 and is headquartered in Jiading, Shanghai. In a few years, through capital-driven + technological innovation, it quickly established a global competitive advantage in the imaging industry. It established the establishment of molecular imaging (MI) and computerized tomography (CT). , Radiotherapy (RT), X-Ray, AI Intelligence and other product divisions.

Through the open talent development platform, hundreds of highly-researched talent teams have gathered in the world. Currently 14 system products and 4 software products for medical imaging equipment operations have been released.

The 96-loop ultra-clear high-speed PET-CT fills the international gap with double breakthroughs in resolution and scanning speed; the industry’s first dynamic multipole 3.0T magnetic resonance end China's hardship in the past decade, making China's first initiative.

The new generation of 112-ring PET-CT, the industry's first dual-mode 128-slice CT and other products are still full of science and technology, and maintain about 18% of R&D investment each year. The medical image unicorn is still moving forward.

Shenzhen Mindray Medical Co., Ltd. was founded in 1991 and started as a trader. proxy The development model of sales+independent R&D+internationalization+domestic and international mergers and acquisitions has established three major production lines of Mindray: monitoring, ultrasound and inspection.

Without exception, the rapid development of Mindray is closely related to the operation of capital. The three major production lines have established cooperation with large multinational corporations.

Guardianship was later acquired by the United States Datascope, Ultrasound was Japan’s Toshiba, the inspection was the United States’s Kurt and Beckman, the technological advantages established through M&A, valued customer value relationships, and internationalized brand operations enabled Mindray in China. medical instruments The industry quickly took the lead in the industry.

Monitors and other products are widely used in high-level hospitals at home and abroad. The development model of three irons has been developing strongly in China, and 10% of annual R&D investment still needs to be improved.

Lepu Medical was founded in 1999, formerly known as Beijing Lepu Medical Instruments Co., Ltd., and is jointly funded by the 725th Research Institute of China Shipbuilding Industry Corporation and the WP Company of the United States. The latter is 'percutaneous cavity and coronary angioplasty'. The two patented technologies and production technologies of the catheters and stents for dilating blood vessels (recognized by the Beijing Science and Technology Commission as high-tech achievements) were evaluated as price contributions.

Lepu Medical has built a strong technical advantage on carrier-free drug stents. Using special techniques to make 300-400 nm microwells on the stent, rapamycin is sprayed into the nanopore, and proprietary techniques are used to enhance drug and nanotechnology. The carrier-free drug stent made by microporous adsorption treatment effectively solves the problem of restenosis within three months after implantation of the bare stent, and avoids the problem of long-term thrombosis of the stent, which has significant clinical effects.

Currently occupying an absolute advantage in this category, the PE price-earnings ratio is 66 times, with a valuation of 55 billion yuan.

Shenyang Neusoft Medical Systems Co., Ltd. was founded in 1998 as a heavy responsibility in carrying the development of medical devices in China. enterprise One of them, the Republican brothers of “Nan'anke North Neusoft” was once highly hoped for by the state. Neusoft did live up to expectations for a long period of time. In the development of high-end equipment such as spiral CT and magnetic resonance, the national medical banner was picked up.

In 1997, Neusoft Medical took the lead in independent research and development of whole body CT, and finally broke the monopoly of international multinational companies. After experiencing numerous sleepless nights, Neusoft Medical innovatively developed a PC replacement array processor. The imaging speed of CT machines was from the initial 58 seconds to 28 seconds, then to 18 seconds, 8 seconds, 5 seconds, and finally until 1 second.

Because of the existence of Neusoft, the price level of the entire CT industry in China as a whole fell by about 30%, directly benefiting the people and the patients.

This has also become a new milestone in the development history of large-scale high-end medical equipment in China. It also marks the end of the era when the core technology of CT products was monopolized by a few foreign companies.

In the field of CT products, it continues to lead the domestic CT industry: the market share of double-row CT is at the front rank; 16-row CT is at the forefront; the first to successfully develop 128-slice spiral CT with independent intellectual property rights in China in 2015, half of the order products enter the domestic top three Hospital, CT category worthy unicorn!

In 1998, Wu Guangming and his father Wu Lianfu jointly founded Jiangsu Yuyue Medical Equipment Co., Ltd., the predecessor of Yuyue Medical. From a township enterprise in southern Jiangsu, under the efforts and wisdom of Wu Guangming and his team, he became a local medical device company. Leader.

From the initial wheelchair, to the later nursing series products, to the medical oxygen supply series, Yuyue Medical has achieved rapid development by expanding its product line.

The Group established the German research and development center of Admiralty Admiralty Germany and successively acquired Germany's largest defibrillator manufacturer Metrax GmbH in Germany. It has invested in Amsino Medical, focusing on R&D + mergers and acquisitions. The categories are increasingly rich: The company has persisted in R&D investment for many years, and the mergers and acquisitions in the past years have been even more successful. To expand the product line.

Acquired Suzhou Medical Products Factory to integrate new Chinese brand-new machines; Acquired Shanghai Machinery Group; Product line extended to surgical instruments, sanitary materials, etc.; medicine , Expanding disinfecting products and services, cooperating with Shanghai Machinery to open up new markets, and other initiatives, will enable Yu Yue to quickly become a unicorn enterprise in the industry for rehabilitation nursing, medical oxygen supply and medical clinical medical devices.

Located in Shenzhen, Nanshan District Yuquan Road Yizhe Building Kaili Biomedical, founded in 2002.

It has created a number of firsts in the Chinese ultrasound industry. Kaili is also the first manufacturer in China to master the core technology of color Doppler ultrasound equipment and B ultrasound equipment. Its color ultrasound technology is at the leading position in the domestic industry, in the international market. The first to enter the barriers of higher European and American markets, the product line is gradually extended from the low to high end.

Open Medical holds more than 20 ultrasound imaging products, with self-produced probes, covering multiple medical fields suitable for ultrasound imaging diagnosis.

At the same time, in the field of electronic endoscopy, the development of domestically produced high-definition electronic endoscopes enables hospitals around them to carry out high-definition endoscopy.

It has 91 invention patents, 62 utility model patents, 51 exterior design patents, 28 non-patent proprietary technologies, and 55 copyrights. It has become an absolute unicorn company in the field of ultrasound technology and products.

Established in 2002, Anjian Technology is a global leader in DR medical device suppliers. For 16 years, it has been deeply cultivating in the DR industry to promote the digitization process of China's universal diagnostics.

Not only that, Anjian Technology actively deployed DR industry technology, focused on product innovation, and pioneered the development of DR dynamic detectors, high-voltage generators and other core technologies in China, and introduced dynamic DR with excellent diagnostics in the world, taking Chinese DR from the traditional Static diagnosis leads to more accurate dynamic diagnosis, effectively reducing misdiagnosis.

It also effectively reduced the price of DR products monopolized by foreign medical giants by 50%, making DR an important diagnostic and diagnostic equipment for counties and grass-roots hospitals in China. The products have achieved 7,000 installed capacity in China, leading the industry. Among them, dynamic DR installed exceeded 2,000 homes. , Became the pioneer and absolute leader in dynamic DR subdivisions.

Dynamic DR's large-format, real-time high-definition spot, visualization, dynamic video playback and storage make the screening diagnostics more accurate and efficient. The products are exported to more than 30 countries in Southeast Asia, Europe, Central Asia, the Americas, and Africa. And the region, is a cutting-edge unicorn in China's DR industry. Became the pioneer and leader of China's dynamic DR industry.

Founded in 1999, Xianjian Technology is an industry-leading provider of minimally invasive interventional medical devices for cardiovascular and peripheral blood vessels.

The products are sold to Europe, South America, Asia, Africa and other places. The market share of congenital heart occluder reaches the second place in the world. The pioneering unicorn road has experienced: imitation-improvement-independent innovation process. Congenital heart Disease occluder is a model of the company's product innovation.

The first generation of Xianjian products is mainly imitation. The second generation of products is based on the first generation of material innovation, using the world's first nano-titanium nitride coating, effectively reducing the release of metal ions to the human body, and can reduce the thrombus Risk formation.

The third-generation occluder improves the product structure and makes operation easier. Currently, the product has been sold in more than 80 countries and has become a leading technology and product in the domestic atrial appendage occluder field.

In 1995, Libang Instrument was established in Shenzhen. With long-term independent research and development and investment, it became the absolute leader in the field of fetal monitoring and ECG products.

Take birth control products as an example, the newly introduced ultrasound Doppler fetal monitoring system FTS-6 - called by the doctor 'hot wheels', FTS-6 ultrasound Doppler fetal monitoring system is first in the fetal monitoring workflow A fundamental change has taken place. One device is worth 8 traditional birth monitors.

In the era of comprehensive second-children's openness, the introduction of this product will have a very significant effect in reducing the workload of obstetrical medical staff and reducing the pressure of maternal hospital visits.

The listing of products will also bring a huge impact to the traditional birth control market, which not only improves the product's competitive advantage, but also promotes the innovation of its own fetal monitoring products.

In the field of ECG, the SE-18 digital 18-lead electrocardiograph is the highest-end ECG product of Ribon. This product is also a very few 18-lead electrocardiographs in the real sense of the industry. Its clinical value lies mainly in the diagnosis of chest pain.

In the field of ECG, Libang Instrument has patented SEMIP ECG automatic measurement and analysis algorithm. This technology has passed the internationally recognized authority ECG database (European CSE database, US AHA database, US MIT database) Level.

Currently, Libon's fetal monitoring and ECG products occupy the first place in the domestic market and become a well-deserved unicorn company in this field.

MicroPort® Medical originated in Shanghai MicroPort Medical Devices (Group) Co., Ltd., established in 1998. More than 260 products are listed on the market, covering cardiovascular intervention, orthopaedic implantation and repair, cardiac rhythm management, electrophysiology, aorta and peripheral blood vessels. Interventional, neurological intervention, diabetes and endocrine management, surgical operations and other ten areas.

MicroPort® medical products have entered more than 5,000 hospitals worldwide, covering major markets such as Asia Pacific, Europe and the Americas. On a worldwide scale, every 12 seconds, a MicroPort® medical product is used to treat patients' lives or improve Its quality of life or used to help it spawn new life.

Among them, the coronary drug stent is the first domestic drug stent system. It has maintained its leading position in the domestic market since its launch in 2004. The world’s first drug-targeted eluting stent system launched in 2014 made Minim® Medical Completed the leap from followers to leaders in the field of coronary stents.

In the field of orthopedic joints, the market share of Minimax® Medical is currently ranked fifth in the world. By specializing in independent innovation, it has a total of more than 3,000 patents (applications), a number of products have won the second prize for national scientific and technological progress and other countries And provincial and ministerial level honors, in Shanghai, China, Jiangsu, Zhejiang, Beijing, Shenzhen and Memphis in the United States have established production and research and development bases.

Through overseas mergers and acquisitions and joint ventures, MicroPort® Medical is gradually advancing the global industrial layout. More than 4,500 of the company’s current employees are overseas employees, and a medical unicorn invisible in China.

Today, the beginning and continuation of medical device companies should not monopolize or profit for the ultimate goal of becoming a unicorn. Instead, they should continue to use innovation as a process to improve human health and make life better. .

Those companies that seem to have a good trend on the surface do not necessarily become unicorns. Likewise, those unicorn companies that are struggling to innovate will also be abandoned by the Unicorn if they deviate from innovation on the road to growth.

Innovation is the only driving force for the progress and development of human society. Innovating enterprises can survive in the era. At the same time, they also change the times through innovation. They have spawned batches of new unicorn companies. Only perseveringly innovate, rely on innovation, and rely on it. A group of Entrepreneurship , The continuous contribution of world-class entrepreneurs who have risen in the field of innovation can truly rejuvenate the national medical industry and realize the great rejuvenation of the Chinese nation.