University of Toronto develops handheld skin 3D printer to quickly repair wounds

A research team at the University of Toronto has developed an innovative 3D bioprinter - a handheld skin 3D printer that can print skin tissue on deep wounds. The printer can form tissue in situ and can be in two minutes or less Completed in time.

In the field of 3D bio-brushing, 3D printing of skin tissue may be one of the most promising applications of this technology. Some of the effective skin tissue regeneration solutions have been extensively tested and approved. However, they are currently used in laboratories. Bioprinter devices tend to be oversized, often quite expensive and complex, which limits its use in clinical applications. The University of Toronto researchers' 3D skin printers can provide solutions to these problems, while being cheap and practical.

Patients with deep wounds usually cause damage to the skin's three layers of skin: the epidermis, dermis, and subcutaneous tissue. The currently preferred treatment is called split-thickness skin grafting, in which healthy donor skin is transplanted to the epidermis and Partial dermis. There is a need for sufficient donor skin to cover the three layers. This method of layer thickness skin grafting is effective, but this is rarely possible. Part of the injury site is usually 'ungrafted' or uncovered. As a result of poor healing results.

The hand-held 3D bioprinter uses tissue paper and a special bio-ink that promotes tissue regeneration. The tissue piece is placed in a specific part of the wound area to form a base for effective regeneration of damaged skin. Bio-ink is composed of Consisting of protein biomaterials, the biomaterials include the most abundant proteinaceous collagens in the dermis and protein fibrin, which is essential for wound healing. The materials of these bio-inks are arranged vertically along the interior of each tissue.

The handheld 3D bioprinter is similar in size to a small shoebox and weighs less than one kilogram (2.2 pounds). The operator needs short training and it eliminates the cleaning and incubation stages that many conventional 3D bioprinters often require. The team hopes that one day their portable 3D bioprinter can be used in clinical applications to completely change the treatment of burns and other major skin wounds.

Source: Tiangong Society