Capsule drugs are the most common type of drug. Many people are confused when taking them. 'What can I do if swallowed? Can I pour the medicine out of the capsule?' Actually, the drug is packed in capsules. Inside, on the one hand, it is for convenience of swallowing, on the other hand there are reasons for efficacy and safety.
The drugs are usually made into capsules for the following reasons: First, they function as a sub-agent and are convenient to take; Second, the drug itself is very bitter or has an odor, capsules can effectively mask the taste of the drug; Third, slow release The capsule can release the drug continuously for a long time, or release the drug slowly at a predetermined speed, so that the blood drug concentration is stable; Fourth, the enteric capsule can prevent the drug from being destroyed by gastric acid, making it weak alkaline condition in the intestine. Absorption, on the one hand, can better play the efficacy, on the other hand can also avoid some of the adverse reactions.
If you take an ordinary capsule drug that functions as a depot, it is generally not much affected by pouring out the capsules, such as Norfloxacin capsules, Cephalexin capsules, Pefifil (Bifidobacterium), etc. However, if the following three types of drugs, it is not recommended to disassemble.
1. Enteric-coated capsules. Drugs that are easily damaged in the stomach and are irritating to the stomach. They are made into enteric-coated capsules. Their capsule shells are insoluble in gastric juices and reach the intestine before they dissolve to release the drug. In order to prevent the drug from being destroyed by gastric acid, or to avoid stimulation of the stomach by the drug, if the forced dismantling is easy to reduce the efficacy of the drug, irritation to the stomach may result in serious stomach bleeding. For example, the minocycline capsule clearly indicates: This product can cause esophageal ulcers when it resides in the esophagus and disintegrates.
2. Drugs with particularly large odors. Some medicines are very odorous and have a bitter taste. Adults are very hard to accept, not to mention children. Taking drugs is easy to cause children's nausea and resentment, resulting in fear of drugs. Commonly used antibiotics Drugs, such as amoxicillin, cephradine, etc., are all bitter in taste. Actually, the medicines given to children nowadays are mostly made into granules and powders, and flavors with large tastes will be properly added to improve taste and taste. Medication discomfort.
3. Sustained-release capsules or controlled-release capsules. These drugs must be swallowed completely in order for the drug to be delivered in a balanced dose and to exert its best efficacy. If taken apart, it will lose its slow-release control function, making the drug short. During the release of a large number of blood drug concentrations increased significantly, and even cause drug poisoning.
