Vitamin supplementation during antibiotics

It is a kind of metabolite produced by microorganisms or higher animals and plants that has anti-pathogens or other activities during the growth process. It is mainly used to treat various bacterial infections or pathogenic microbial infections. There are many departments in the hospital, There are many kinds of drugs, but antibiotics are used in various departments and various diseases. Antibiotics have ranked first in China for consecutive years in total sales, accounting for nearly 1/3 of national pharmaceutical sales, which shows its importance in the medical field. Everyone is familiar with antibiotics, more or less taking, but it is not necessarily clear that the link between antibiotics and vitamin deficiency. In fact, long-term, high-dose antibiotics, it is best to add some vitamins, specific can be divided For the following two situations.

Use certain antibiotics to supplement B vitamins, vitamin K. E. coli in the human intestine has a synthetic B vitamin, vitamin K, and penicillin, amoxicillin, cefixime, ceftriaxone, cefoperazone, ring Profloxacin, azithromycin, clarithromycin, minocycline, doxycycline, rifampin, etc. Excretion of antibiotics from the biliary tract inhibits or kills bacteria in the gut and indirectly impairs the synthesis of these two types of vitamins. Causes dry mouth, mouth ulcers, sore throat, dermatitis and other symptoms of deficiency of B vitamins, may also be caused by the inhibition of synthesis of vitamin K resulting in hypoprothrombinemia or bleeding. The above situation, can be used in combination B vitamins and vitamin K to prevent, especially the elderly population, extremely debilitating patients, liver and kidney dysfunction, but also pay attention to supplement.

Vitamin C can be supplemented properly during antibiotics. Vitamin C and antibiotics have a synergistic antibacterial effect. According to reports, when acute and chronic infections occur in the body, the content of vitamin C in leukocytes drops sharply, which reduces the ability of white blood cells to fight pathogens. When the content of vitamin C in the body is high, white blood cells are more active, and the ability to clear pathogens is stronger. Vitamin C is also an essential auxiliary substance for collagen synthesis. Adequate vitamin C can indirectly increase the barrier function of organism tissues to external pathogens; It also induces interferon production in vivo, enhances resistance to viruses and bactericidal function of neutrophils.

However, it should be noted that vitamin C is an acidic substance and that some antibiotics may reduce their efficacy when taken together with them, such as isoniazid, aminoglycosides and sulfa drugs. If the condition needs to be taken at the same time, the two should be separated by 2 hours.

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