It is clinically common for patients to stop taking drugs without authorization. Some patients may be discontinued because of their improved condition, and some patients are worried about the long-term side effects of taking drugs. They will not eat for some time. In fact, some drugs that need to be taken long-term, if not Suddenly disabled by a doctor's instruction may cause the recurrence of the original disease or 'rebound'. For example, the following drugs:
Glucocorticoids, such as prednisone, dexamethasone, etc. Sudden withdrawal of long-term medication can cause the disease to rebound, or infection, trauma, bleeding, etc., induced adrenal crisis, manifested as nausea, vomiting, muscle weakness, Hypoglycemia, shock, coma and even life-threatening. Prolonged use of these drugs should be slowly reduced to within 15 days of withdrawal.
Antihypertensive drugs. After taking antihypertensive drugs, sudden withdrawal of medication if blood pressure is normal can lead to a dramatic increase in blood pressure within a short period of time, even beyond pre-treatment levels. Dizziness, headaches, insomnia, blurred vision, and blood pressure rebound Crisis symptoms. Antihypertensive drugs need to adhere to long-term use.
Antiarrhythmic drugs. Long-term use of antiarrhythmic drug propranolol, if the sudden withdrawal of the drug will appear to increase heart rate, blood pressure, angina, symptoms of aggravation phenomenon. If you stop the drug, it should be gradually reduced to withdrawal.
Hypoglycemic drugs. If you think that the recent sudden blood glucose normal interruption of medication, can make blood sugar swell, or even ketoacidosis coma. If the doctor does not adjust the treatment plan, hypoglycemic agents also need to long-term use.
Antiepileptic drugs. Long-term use of phenobarbital, phenytoin sodium, if sudden withdrawal can occur, or even lead to epileptic seizures, and in a state of epilepticus. When you need to stop the drug, you should gradually reduce the amount of drug withdrawal in 15 days .
Finally, we must remind everyone that when decommissioning or changing long-term use of drugs, it is necessary to take a gradual method of reduction. When the need to change drugs, it should also take a gradual transition method, that is, first add new drugs based on the original drug, gradually The original drug is decremented until it is deactivated. The original drug should still be available during discontinuation. Once the phenomenon of 'rebound' occurs, it can be used again.
