Many hypertensive patients how to take medicine and blood pressure control is not good.This is not necessarily the reason for the drug, may be related to the patient's medication habits.If the wrong time to take medicine, it is not conducive to antihypertensive drugs play a role.
To master the correct medication time, we must first understand their own blood pressure.
For most people, blood pressure has a rhythm of daytime high and low night, two peaks and one valley within 24 hours: 8: 00-9: 00 and 16: 00-18: 00. During nighttime sleep, Blood pressure dropped to 0:00 to 3:00 to reach the lowest one day blood pressure curve like a spoon, called spoon-type blood pressure.According to this law, so that the antihypertensive drugs and blood pressure fluctuations in the peak time of the basic synchronization Can make drugs produce better antihypertensive effect.Specific for the spoon-type blood pressure patients should follow the following points:
1. Take a long-term antihypertensive drugs (including controlled release tablets and sustained release tablets) taken once a day, such as amlodipine, nifedipine controlled release tablets, metoprolol sustained release tablets, perindopril, valsalone Tanzania, losartan, fosinopril, benazepril, etc., and more in the morning 7:00 medication.After meals can be, it is recommended before taking food.
2. Take 2 times a day in the effective antihypertensive drugs, such as nifedipine sustained release tablets, enalapril, felodipine (methotrexate), metoprolol, etc., 7:00 in the morning and 15:00 Take medicine as well.
3. take 3 times a day short-acting antihypertensive drugs, such as nifedipine tablets, captopril tablets, wake up the first morning service, the second noon 13:00 service, the last time before 18:00 clothes.
4. Also need to be reminded that spoon-type blood pressure patients should not take antihypertensive drugs before going to bed or at night to avoid hypothyroidism caused tissue perfusion, resulting in ischemic stroke.In addition, diuretics such as hydrochlorothiazide should be taken in the morning, Lest night use caused by increased nocturia, affecting sleep.
In addition, some patients with blood pressure fluctuations are not typical, nocturnal decrease in blood pressure less than 10% compared with daytime, known as non-spoon-type blood pressure; there are fewer patients with nocturnal blood pressure without falling or overtaking the daytime situation, was In general, non-spoon-type or anti-spoon-type blood pressure patients often suggest the existence of continuous sympathetic stimulation, causing blood pressure continued to rise at night, will the brain, heart, kidney and macrovascular harm, therefore To closely control nighttime blood pressure, such patients need to use long-acting antihypertensive drugs, should be at 8 o'clock or bedtime medication.
The patient is best to do a 24-hour blood pressure monitoring, according to the type of blood pressure fluctuations to determine the medication time, usually choose 1 to 2 hours before peak medication. Patients can also choose one of four time points, once every 6 hours to measure blood pressure, continuous Measured three days, we can roughly grasp their own blood pressure fluctuations, which can infer the appropriate medication time.
