Patient Mr. Liu: I am 44 years old and have a stent implanted in the coronary artery for acute myocardial infarction 3 months later, after long-term aspirin, metoprolol succinate, atorvastatin calcium and clopidogrel, etc. Before the stent, I had a history of 5 years of hypertension, I had been taking enalapril hydrochloride and amlodipine besylate tablets regularly, but my blood pressure was stable, but in the last month, I found that there was a problem with my erection. Is it due to the drug? Is there any way to improve?
Liu Zhijun, chief pharmacist at Beijing Anzhen Hospital, Capital Medical University: Many young men who are young men and women will find themselves gradually losing their blood pressure due to high blood pressure, hyperlipidemia and coronary heart disease after eating a pile of cardiovascular drugs In fact, this should be done in terms of both disease and medicine.
There are many factors that affect the sexual function of cardiovascular disease itself.Erectile dysfunction can be caused by one or more diseases and risk factors, common diseases including hyperlipidemia, hypertension, diabetes, cardiovascular and cerebrovascular diseases, trauma, etc. And mental health, medicine, lifestyle and social environmental factors related to the study found that over 40-year-old male patients with hyperlipidemia and erectile dysfunction.Hypertension and erectile dysfunction have common risk factors, such as smoking , Hyperlipidemia, obesity, etc .. Coronary heart disease and erectile dysfunction often also exist, about 50% to 70% of patients with coronary heart disease also suffer from sexual dysfunction.
Drugs may lead to erectile dysfunction.Current cardiovascular disease and erectile dysfunction, the findings are inconsistent.According to the highest level of evidence in meta-analysis of the results, combined with clinical experience and everyone's consensus, generally considered to reduce sexual function Cardiovascular drugs are: atenolol, metoprolol, carvedilol, hydrochlorothiazide, spironolactone, digoxin; can improve sexual function are: Nebivolol, valsartan, losartan, Sartan, atorvastatin, simvastatin.
For Mr. Liu, I would first like to suggest that he should avoid choosing drugs that affect sexual function, such as enalapril hydrochlorothiazide. If Nebivolol (currently not listed in the domestic market), you can give priority to or choose to improve sexual function Valsartan, losartan and so on.
Patients should actively treat the primary disease, such as hypertension, hyperlipidemia, diabetes, etc. The primary disease for erectile dysfunction is much larger than the impact of its treatment of drugs, cardiovascular disease can not be discontinued drugs, 'life is not, From 'adjust the treatment program to consult a pharmacist or doctor, not privately exchange.
Need to be reminded that some, such as sildenafil treatment of erectile dysfunction drugs, and some cardiovascular drugs (especially nitrates) will fight, ban combined, the patient can not add their own casually, to consult a pharmacist or Doctor, use with caution.