Spectral Mass Spectrometry Laboratory researchers designed a simple ultrasonic atomization device for the rapid and efficient extraction of VOCs from micro-urine. By combining with the independently developed mass spectrometer PTR-MS, the rapid and rapid development of VOCs in urine droplets And highly sensitive monitoring.
Recently, the Center for Mass Spectrometry and Mass Spectrometry at the Medical Physics Center made progress in body fluid testing and developed the technology of UNE-PTR-MS to detect the presence of volatile organic compounds (VOCs) in urine Highly sensitive and rapid detection, the findings are published in Analytical Chemistry (DOI: 10.1021 / acs.analchem.7b04563).
Urine VOCs reflect the metabolic status of the human body or disease characteristics, before the urine VOCs measurement methods, there are some flaws: either slow or large amount of urine.To this end, spectral mass spectrometry laboratory researchers designed a simple The ultrasonic atomization device is used for rapid and efficient extraction of VOCs in micro-urine, and the rapid and sensitive monitoring of VOCs in urine droplets can be achieved through the combination with PTR-MS, a self-developed mass spectrometer. , Second order response time and nanogram level detection limit and so on, will play a role in the detection of body fluid disease markers, but also can be used for rapid detection of volatile matter in the environment of water.
The research has been funded by the National Natural Science Foundation of China and other projects. The devices and methods used have been authorized by the national invention patent.
