Affiliated Zhongda Hospital of Southeast University cardiovascular chief physician Chen Lijuan
Statins are commonly used to lower cholesterol drugs, can control blood lipids, stabilize plaque, reduce the risk of cardiovascular disease, but like to drink or more people who entertain more after drinking to eat statins, we must be cautious.
People who have a history of alcohol abuse do have a real risk of taking statins because one of the potential side effects of statin therapy is to damage the liver by regulating the expression of liver lipase to achieve lipid-lowering effects that already affect liver function and then drink heavily , Will further damage the liver.Liver problems may not show any obvious symptoms, only through the liver function test out.
Alcohol at night will reduce the efficacy of statins by inhibiting the synthesis of cholesterol in the body, play a role in lowering blood cholesterol. The peak of human cholesterol synthesis is at night, so the conventional statin medication time before going to sleep Compared with drinking during the day, alcohol and medication at night time interval is shorter, the impact of drugs greater.
It is recommended that patients taking statins should not drink alcohol, and women who can not afford alcohol add one drink per day, up to two cups a day for men (one serving of 340 grams of beer, 142 grams of wine, or 43 grams of spirits). Before taking statins, check the liver function, and then consider whether to take, such as abnormalities to be discontinued, and immediately consult a doctor .If the patient to be with the clothes itraconazole, ketoconazole, erythromycin, carat Gentamicin, gemfibrozil, gemfibrozane, danazol and so on, heart disease patients may also take amiodarone, verapamil, diltiazem and other drugs, but also increase the side effects of statins, Therefore, the doctor should tell the history of medication.
