Artemisia annua raw materials international market cold

Artemisinin is the first anti-malarial drug invented by Chinese medical researchers after the founding of new China and is one of the most prestigious antimalarial drugs in the international pharmaceutical industry, which is developed by Chinese scientists independently developed and possessed intellectual property Once the artemisinin produced in China has been unveiled and succeeded, the United Nations Department of Health (DH) no longer procures those useless quinine antimalarial drugs, but purchases artemisinin to distribute it to malaria patients in Africa Use .2004 World Health Organization officially announced: the elimination of antimalarial drugs in the first line of chloroquine and Berkui two old products, and artemisinin as a first-line antimalarial products recommended to the national clinical community. This is the Chinese medicine again in the international The medical stage is shining.

This is undoubtedly a huge 'cake' for artemisinin producers because of the large number of malaria patients in the world. The main medicinal plants for the extraction of artemisinin are Artemisia annua. In 2004, artemisinin in international medicine The world market in several provinces set off a boom in planting Artemisia annua, because in accordance with the conventional amount of calculation, the international market demand for artemisinin the most conservative estimate of about 250 tons, for which China's Chongqing Youyang county government will plant Artemisia annua as the main way to help local farmers get rid of poverty to become rich.To 2014, Youyang County, the county planted 8 million mu of Artemisia annua, according to a conservative estimate of these Artemisia annua extract at least 60 tons of artemisinin finished product. Yang, Hubei Enshi Tujia Autonomous Prefecture has also become the main cultivation base of Artemisia annua L. Because the Artemisia annua produced here is higher with artemisinin. At present, the lowest planting of Artemisia annua can also extract 20 to 30 tons of artemisinin In addition, Hunan, Guangxi, Fujian and Zhejiang provinces and other provinces also have a certain amount of Artemisia annua planted area.

Relevant departments estimate that the actual production of artemisinin in the 110 tons.With the rise of the national 'artemisinin hot', more than a decade ago around the country about more than 100 plant extracts processing plant engaged in artemisinin production But the artemisinin hot too fast to go too fast, because at that time Artemisia annua in short supply, some illegal farmers will be mixed with yellow grass powder in Artemisia annua powder to provide artemisinin production plant caused by high impurities and low quality and other consequences. The international market artemisinin poor sales, so the final Chinese artemisinin API in the international market sales decline, a lot of artemisinin extraction processing plant so closed.

Another important factor contributing to the poor sales of domestic artemisinin in the international market is that the climate soils of these countries, such as India, Vietnam, Thailand and Indonesia, are also suitable for planting Artemisia annua, and the labor costs of these countries are significantly lower In recent years, India, Vietnam is also vigorously promote the cultivation of Artemisia annua and export artemisinin crude drug crude foreign manufacturers and even directly in India and Vietnam to set up factories, from the Artemisia annua extract crude artemisinin and then shipped back to the national processing , Thus giving up in China purchase Crude artemisinin.

It is precisely because China's neighboring countries took away the Chinese artemisinin producers 'rice bowl', eventually leading to a large number of domestic artemisinin extraction processing plant failure.According to the relevant domestic departments estimate that in recent years, China has about 70% Artemisinin extraction processing plant closed. There is news that the current production of artemisinin in the international market accounted for only about 5% share, while India is behind, its artemisinin products in the international market accounted for a large proportion. Novartis and Sanofi, the two major Western pharmaceutical companies, at a very low price to buy India or Vietnam, artemisinin crude goods shipped back to Europe for finishing, and then processed into artemisinin compound preparations sold to the African malaria area In this way, from Artemisia annua growers to artemisinin extract processing plants, the artichoke artemisia of China caused a devastating blow to the whole industry chain, which is why in recent years, domestic artemisinin raw materials in the international market, the real cold the reason.

Artemisinin international market volatility, the current large members of artemisinin is the United Nations Department of Health, they are responsible for ordering artemisinin preparations and distributed to the southern African malaria epidemic area of ​​the national use of patients, but the reality is that the incidence of malaria also has peak and In the event of a high incidence of malaria, the United Nations will issue large quantities of artemisinin preparations to Africa, and once the drought in Africa is low and the density of mosquitoes is reduced and the incidence of malaria is reduced, the United Nations Department of Health The amount of artemisinin is also reduced, so the artemisinin market has obvious volatility. The United Nations Department of Health mainly ordered the Swiss Novartis and France Sanofi company 2 production of artemisinin compound preparation .In recent years, India imitation artemisinin compound Preparations have also officially debut international medicine Market and take away some of the Western company's artemisinin market.This is the artemisinin industry chain is even more bad news, because India's exports of various formulations are very low prices. Domestic news that India imitation Artemisia annua The compound formula has accounted for 50% of the international artemisinin market.

As for the market outlook for artemisinin, malaria has a significant reduction in the incidence of malaria in South-East Asia as the artemisinin is used in South-East Asia, with two high-calorie areas of malaria, southern and southeastern Africa, Widespread poverty, so malaria is still threatening local residents health Mian disease , And the local government is unable to change the status quo, can only wait for the United Nations bailout.In fact, the United Nations Department of Health to buy antimalarial drugs mostly from the Western developed countries, government sponsorship, since the United Nations took the Western countries donations, the organization Will certainly give priority to the order of Western pharmaceutical manufacturers to produce artemisinin products for distribution to African countries. This will explain why the Kunming Pharmaceutical Factory in China and Guilin pharmaceutical companies can also produce qualified artemisinin preparations and quality assurance , And the United Nations Department of Health is willing to spend a high price of Novartis and Sanofi company's artemisinin products, the reason is self-evident.Therefore in the next few years, unless the malaria again pandemic, China's artemisinin industry will further fall into the trough.